Shikonin- chinhu chitsva chinorwisa mabhakitiriya chinokonzeresa shanduko yemishonga
Munguva pfupi yapfuura, masayendisiti akawana chinhu chitsva chinorwisa mabhakitiriya, shikonin, mudura rehupfumi hwezvirimwa. Kuwanikwa uku kwamutsa kutarisisa uye kufara kwepasirese. Shikonin ine wide-spectrum antibacterial chiitiko uye inotarisirwa kuve yakakosha mumiriri wekugadzirwa kwemishonga mitsva yemishonga. Shikonin inotorwa kubva muchirimwa chinonzi comfrey, chinokura mumativi eAsia, Europe, uye North America. Shikonin ine ruvara rwepepuru rwakajeka uye inoshandiswa zvakanyanya mudhayi nemishonga yemakwenzi. Zvisinei, tsvakurudzo yazvino inoratidza kuti shikonin haisi yakanaka chete, asiwo inogona kuva antibacterial agent.
Mukuedza, masayendisiti akawana kuti shikonin ine inhibitory yakasimba pane zvakasiyana-siyana zvebhakitiriya uye fungi. Kwete izvozvo chete, zvinogona zvakare kuve nehutachiona hwehutachiona kune mamwe mabhakitiriya asingarapike nemishonga, ayo ane kukosha kukuru kune dambudziko razvino rekurwisa mishonga inorwisa mabhakitiriya. Vatsvakurudzi vakawanawo kuti shikonin inogona kushandisa maitiro ayo antibacterial nekuparadza bacterial cell membrane uye kudzivisa kukura kwayo. Iyi nzira yakasiyana nemishonga inorwisa mabhakitiriya iripo, iyo inopa nzira itsva yekugadzirwa kwemishonga inorwisa mabhakitiriya. Kuti uwedzere kuona kushanda uye kuchengetedzeka kweshikonin, vaongorori vakaita nhevedzano ye in vivo uye in vitro kuyedza.
Chinhu chinonakidza ndechekuti shikonin yakaratidza yakanaka biological chiitiko pasina kukonzera yakakomba mhedzisiro. Izvi zvinoita kuti shikonin ive inogona kuita antibacterial agent uye inopinza hutsva hutsva mukutsvaga nekuvandudzwa kwemishonga inorwisa mabhakitiriya. Kunyange zvazvo kuwanikwa kweshikonin kwakaunza tariro, masayendisiti anoyeuchidzawo vanhu kuti kugadzirwa uye kushandiswa kwemishonga inorwisa mabhakitiriya inofanira kungwarira. Kushandiswa zvisizvo uye kunyanyoshandiswa kwemishonga inorwisa utachiona kwakakonzera dambudziko repasi rose rekuramba zvinodhaka, saka mishonga mitsva inorwisa mabhakitiriya inofanira kushandiswa nekutarisirwa zvine musoro.
Pamusoro pezvo, vesainzi vakadaidzirawo kune vanoisa mari pamwe nehurumende kuti vawedzere mari nerutsigiro rwekutsvagisa nekuvandudzwa kwemishonga inorwisa mabhakitiriya kusimudzira kugadzirwa kwemishonga mitsva. Parizvino, kutsvagisa nezve shikonin kwakakwezva kutarisisa kwepasirese. Makambani akati wandei emishonga uye masangano ekutsvagisa ari kuwedzera kutsvagisa nekuvandudza kweshikonin-ane hukama neantibacterial agents.
Vatsvakurudzi vakati vacharamba vachidzidza maitiro e-molecular uye maitiro ekuita kweshikonin kuitira kuti vaongorore zviri nani kukwanisa kwayo. Nekufambira mberi kunoenderera mberi mumunda wemishonga inorwisa mabhakitiriya, kuwanikwa kweshikonin kwakapinza simba idzva mukuchinja kwemishonga inorwisa mabhakitiriya. Inopa tariro uye inoisa hwaro hwechizvarwa chitsva chemishonga inorwisa utachiona. Tinogona kuona kuti tsvakurudzo ye shikonin ichakurudzira hutsva mumunda wemishonga uye kuunza dzimwe sarudzo uye tariro kune hutano hwevanhu.
Nguva yekutumira: Jul-27-2023
